The effect of desalivation upon pulpal function and dental caries in rats.

The role of pulp and saliva in caries susceptibility and resistance was evaluated using a combination of endodontic treatment and desalivation. Evidence was presented that the pulp plays a major role in caries susceptibility. It is suggested that pulpal function is modified by hormonal factor(s) originating from salivary glands. In the rat, saliva appears to play a minor role in resistance to caries.