Van Swol R L, Gross A, Setterstrom J A, D'Alessandro S M
J Periodontol. 1980 Jan;51(1):20-4. doi: 10.1902/jop.1980.51.1.20.
In recent years evidence in the literature has indicated that the immune response may play an important role in the initiation and progression of the periodontal diseases. A study was initiated to determine the IgA, IgG, and IgM concentrations in the granulation tissue removed from deep infrabony pockets of patients with periodontosis and advanced periodontitis. Comparison of mean immunoglobulin levels between the periodontosis and periodontitis groups revealed a statistically significant increase (P less than 0.05) for IgG in the granulation tissue from the periodontosis group. The possible implications of these findings are discussed.
近年来，文献中的证据表明免疫反应可能在牙周疾病的发生和发展中起重要作用。开展了一项研究，以测定从牙周变性和晚期牙周炎患者深骨下袋中取出的肉芽组织中的IgA、IgG和IgM浓度。牙周变性组和牙周炎组之间平均免疫球蛋白水平的比较显示，牙周变性组肉芽组织中的IgG有统计学显著升高（P小于0.05）。讨论了这些发现的可能意义。
