Angiolymphoid hyperplasia with eosinophilia (Kimura's disease).

Angiolymphoid hyperplasia with eosinophilia (Kimura's disease) primarily affects the skin of the head and neck and the oral mucosa. While the clinical picture is nonspecific, the variable microscopic tissue pattern often is diagnostic. The etiology is unknown, and treatment is unpredictable. A case is presented in which Kumura's disease was not suspected clinically prior to the biopsy. The patient responded to topical fluocinonide, and there was no evidence of an immunologic defect.