Kolonel L N, Hirohata T, Chappell B V, Viola F V, Harris D E
J Natl Cancer Inst. 1980 Apr;64(4):739-43.
A retrospective cohort study was performed in Hawaii among 4,779 male shipyard workers exposed to asbestos and 2,757 similar male workers without known asbestos exposure. Observed deaths from cancer and other causes in the 2 groups were compared with expected deaths on the basis of the general population of Hawaii by the use of a modified life-table method of analysis. A risk ratio for lung cancer of 1.7 was found for the exposed group after 20 or more years of follow-up. No increased risk for lung cancer was seen in the nonexposed group. These findings could not be attributed to differences in smoking habits in the 2 shipyard groups or between the shipyard groups and the general population. Because the maximum duration of follow-up for this analysis was 24 years, greater risks for lung cancer may be seen in the exposed group when the follow-up period is extended.
在夏威夷对4779名接触石棉的男性造船厂工人和2757名无石棉接触史的类似男性工人进行了一项回顾性队列研究。采用改良寿命表分析方法,将两组中观察到的癌症及其他原因导致的死亡人数与基于夏威夷普通人群的预期死亡人数进行比较。经过20年或更长时间的随访,发现接触组肺癌的风险比为1.7。未接触组未发现肺癌风险增加。这些发现不能归因于两个造船厂组之间或造船厂组与普通人群之间吸烟习惯的差异。由于本次分析的最长随访时间为24年,随访期延长后,接触组可能会出现更高的肺癌风险。