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什么是分流?中心分流和有效流量的概念以及一种用于以图形方式呈现循环量及其相互关系的方法。

What is a shunt? Concepts of central shunts and effective flow and a method for graphical presentation of circulatory quantities and their interrelations.

作者信息

Zetterqvist P

出版信息

Ups J Med Sci Suppl. 1980;28:1-32.

PMID:6929619
Abstract

The terminologies commonly used in descriptions of abnormal patterns of blood flow in patients with congenital heart defects are valid only in the case of simple abnormal communications in an otherwise essentially normal cardiac anatomy. In more complex cases the expressions are unambiguous and elucidatory only when qualified further, but then the terminology becomes cumbersome. Much might be gained in clarity by considering the combined ventricular output as having four components: two are essential, and equal in size; they constitute the effective flows to the systemic and pulmonary arterial trees of blood from the pulmonary and systemic veins, respectively. The other two are recirculated systemic and pulmonary flows and may or may not exist; they may be referred to as blue and red shunts, respectively. Here, 'shunt' is defined as a by-pass of the capillary system to which a given blood flow is destined. The red and blue shunts are both central--as distinct from peripheral ones, where the by-pass links arteries and veins in one of the two circulations. Adoption of the concepts of central shunts and effective flow as defined here would facilitate a rational and consistent quantitative analysis of the circulation in individual cases irrespective of variations in cardiac anatomy. It would also make it possible to present in instantly understandable diagrams the magnitudes and interrelations of such variables as the oxygen consumption, the blood's oxygen capacity and the oxygen contents of the blood in the great vessels connecting the heart and the two circulations, the combined ventricular output and its components, the mean pressure difference across the pulmonary circulation and the pulmonary vascular resistance. A graph blank for such a presentation is proposed, and its application in cases with and without central shunts is exemplified.

摘要

先天性心脏缺陷患者血流异常模式描述中常用的术语仅适用于心脏解剖结构基本正常的简单异常交通情况。在更复杂的病例中,这些表述只有在进一步限定后才明确且具有阐释性,但此时术语会变得繁琐。通过将联合心室输出视为具有四个组成部分,清晰度可能会有很大提高:其中两个是必不可少的,且大小相等;它们分别构成从肺静脉和体静脉流向体循环和肺动脉树的有效血流。另外两个是体循环和肺循环的再循环血流,可能存在也可能不存在;它们可分别称为蓝色分流和红色分流。这里,“分流”定义为给定血流本应流向的毛细血管系统的旁路。红色和蓝色分流均为中心性分流——与外周分流不同,外周分流是指在两个循环之一中动脉与静脉之间的旁路连接。采用此处定义的中心分流和有效血流概念将有助于对个体病例的循环进行合理且一致的定量分析,而不论心脏解剖结构的差异如何。这还将有可能以易于理解的图表呈现诸如氧消耗、血液氧容量、连接心脏和两个循环的大血管中血液的氧含量、联合心室输出及其组成部分、肺循环平均压差和肺血管阻力等变量的大小及相互关系。本文提出了用于此类呈现的空白图表,并举例说明了其在有和没有中心分流病例中的应用。

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