Fries R, Platz H, Wagner R R, Stickler A, Grabner H, Kränzl B, Krekeler G, Kriens O, Leijhanec J, Mehnert H, Scharf F, Schroll K, Schulz P, Waldhart E, Wepner F, Zisser G
J Maxillofac Surg. 1980 Feb;8(1):25-37. doi: 10.1016/s0301-0503(80)80070-1.
The prognostic significance of so-called organ sites was investigated in 585 cases with carcinoma of the oral cavity and lips. For the subsamples studied the numerical distribution of TNM categories, life tables and life table comparisons were computed. This produced the following results: 1. There is no demonstrable difference in prognosis between identical T catagories in the organs of the oral cavity. 2. In some cases there is a significant difference between identical N categories in organs of the oral cavity. In the No category this is, however, attributable to the substantial differences in the numerical distribution of T categories. By contrast, a logical explanation for the computationally demonstrable significant differences in the Nx category is not available. The problem is currently being investigated. 3. An assessment of identical TN combinations in the "organs" of the oral cavity proved to be impossible on account of the inadequate number of cases available. The so-called "organ localization" of primary tumours in the oral cavity need not - at least for the time being - be accorded any prognostic relevance. The findings should, however, be re-examined on the basis of greater numbers.
在585例口腔和唇部癌患者中，研究了所谓器官部位的预后意义。对于所研究的子样本，计算了TNM分类的数值分布、生命表和生命表比较。结果如下：1.口腔各器官中相同T分类的预后无明显差异。2.在某些情况下，口腔各器官中相同N分类之间存在显著差异。然而，在N0分类中，这归因于T分类数值分布的实质性差异。相比之下，对于Nx分类中通过计算可证明的显著差异，目前尚无合理的解释。该问题目前正在研究中。3.由于可用病例数量不足，无法对口腔“器官”中相同的TN组合进行评估。口腔原发性肿瘤的所谓“器官定位”——至少目前——无需赋予任何预后相关性。然而，这些发现应在更多病例的基础上重新审视。
