Atypical leukemia--relation to chronic myelomonocytic leukemia.

An autopsy case of a 71-year-old man with atypical leukemia was reported. The interesting points in this case were the followings: (1) three clonal proliferations; granulocytic, monocytic, megakaryocytic; (2) abnormality of several kinds of blood cells; (3) phagocytosis of granular leucocytes within megakaryocytes; (4) elevation of anti-EB virus antibody, and (5) detection of herpes-type virus-like particle in the nucleus of monocytoid cell in peripheral blood. Relationship between atypical leukemia and chronic myelomonocytic leukemia was also discussed.