Pongratz D
Microsc Acta Suppl. 1980;Suppl 4:38-43.
This report deals with morphometric investigations of muscle biopsies using a semiautomatic manual analysis system. Examples for differential diagnostic value of metric results are described: 1) Different distribution curves of muscle fibers are helpful in differentiating between two important groups of muscle diseases, chronic polymyositis and muscular dystrophy. 2) Some groups of disorders (e.g. interstitial myositis, neurogenic atrophy) may be subtyped by metric data. 3) Several diseases (e.g. myotonic dystrophy) are characterized by selective atrophy of one fiber type only in distinct muscle groups.
本报告涉及使用半自动手动分析系统对肌肉活检样本进行形态测量研究。文中描述了测量结果在鉴别诊断方面的价值示例:1)肌纤维的不同分布曲线有助于区分两组重要的肌肉疾病,即慢性多发性肌炎和肌营养不良症。2)某些疾病组(如间质性肌炎、神经源性萎缩)可通过测量数据进行亚型分类。3)几种疾病(如强直性肌营养不良症)的特征是仅在特定肌肉群中出现一种纤维类型的选择性萎缩。