Wessberg G A, Epker B N, Bordelon J H, Hyer R L
J Maxillofac Surg. 1980 Aug;8(3):187-94. doi: 10.1016/s0301-0503(80)80099-3.
Medical advances in the care of individuals with sickle cell disease have progressed to the level where elective surgical procedures can be performed. Successful management of these individuals requires understanding of the pathophysiology of the disease in conjunction with specific anaesthetic and surgical considerations. The clinical relevance of these factors are discussed as they relate to haematological, anaesthetic, and surgical management of a young black male who underwent a modified LeFort I osteotomy with segmentalization and genioplasty to correct a severe dentofacial deformity secondary to sickle cell gnathopathy.
镰状细胞病患者护理方面的医学进展已达到可以进行择期外科手术的水平。对这些患者的成功管理需要结合特定的麻醉和手术考量来理解该疾病的病理生理学。本文讨论了这些因素与一名年轻黑人男性的血液学、麻醉和手术管理的相关性，该患者接受了改良的LeFort I型截骨术、分段截骨术和颏成形术，以纠正镰状细胞性颌骨病继发的严重牙颌面畸形。
