通过15N核磁共振光谱法测定二甲基亚砜溶液中鸟苷、胞苷、腺苷和尿苷的自缔合及碱基配对情况。
Self-association and base pairing of guanosine, cytidine, adenosine, and uridine in dimethyl sulfoxide solution measured by 15N nuclear magnetic resonance spectroscopy.
作者信息
Dyllick-Brenzinger C, Sullivan G R, Pang P P, Roberts J D
出版信息
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5580-2. doi: 10.1073/pnas.77.10.5580.
Abstract
The self-association of guanosine, cytidine, and adenosine and base pairing between guanosine, cytidine, adenosine, and uridine in dimethyl sulfoxide have been investigated by the variation of their 15N NMR chemical shifts with concentration and temperature. Guanosine, cytidine, and adenosine all showed evidence of self-association by hydrogen bonding. In guanosine/cytidine mixtures, a hydrogen-bonded dimer is formed; however, no base pairing could be detected with adenosine/cytidine or adenosine/uridine mixtures.
摘要
通过15N核磁共振化学位移随浓度和温度的变化，研究了鸟苷、胞苷和腺苷在二甲基亚砜中的自缔合以及鸟苷、胞苷、腺苷和尿苷之间的碱基配对。鸟苷、胞苷和腺苷均显示出通过氢键自缔合的证据。在鸟苷/胞苷混合物中，形成了氢键二聚体；然而，在腺苷/胞苷或腺苷/尿苷混合物中未检测到碱基配对。
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Nature. 1953 Apr 25;171(4356):737-8. doi: 10.1038/171737a0.
2
NMR evidence of specific base-pairing between purines and pyrimidines.嘌呤与嘧啶之间特定碱基配对的核磁共振证据。
Biochem Biophys Res Commun. 1966 Apr 19;23(2):194-201. doi: 10.1016/0006-291x(66)90527-4.
3
Association by hydrogen bonding of free nucleosides in non-aqueous solution.非水溶液中游离核苷通过氢键的缔合作用。
J Mol Biol. 1966 Jan;15(1):220-31. doi: 10.1016/s0022-2836(66)80222-x.
4
Proton magnetic resonance studies of self-association and metal complexation of nucleosides in dimethyl sulfoxide.
J Am Chem Soc. 1968 Sep 11;90(19):5069-74. doi: 10.1021/ja01021a003.
5
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6
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J Am Chem Soc. 1977 Feb 2;99(3):714-8. doi: 10.1021/ja00445a009.
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