Dawes P J
Br J Cancer Suppl. 1980 Apr;4:14-6.
Between 1st January 1968 and 31st December 1973, 686 cases of squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx and larynx were referred to the Radiotherapy Departments in Newcastle upon Tyne. Cases have been evaluated at either or both of the one and three month post-treatment visits. Of those patients who completely responded by three months, 27% died due to their malignancy. 23% of these cases recurred within the treated volume. By contrast, of those patients who failed to show a complete response at three months, 87% died due to their malignancy and 84% failed to achieve local control. Possible ways in which this information might affect management of the patient and future clinical studies are briefly discussed.
1968年1月1日至1973年12月31日期间，686例口腔、口咽、下咽和喉鳞状细胞癌患者被转诊至泰恩河畔纽卡斯尔的放疗科。在治疗后1个月和3个月的随访中对病例进行了评估。在3个月时完全缓解的患者中，27%死于恶性肿瘤。这些病例中有23%在治疗区域内复发。相比之下，在3个月时未显示完全缓解的患者中，87%死于恶性肿瘤，84%未能实现局部控制。简要讨论了这些信息可能影响患者管理和未来临床研究的可能方式。
