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扁桃体淋巴细胞对新合成DNA的排泄。

Excretion of newly synthesized DNA by tonsil lymphocytes.

作者信息

Staub M, Antoni F

出版信息

Nucleic Acids Res. 1978 Aug;5(8):3071-9. doi: 10.1093/nar/5.8.3071.

Abstract

The main part of newly synthesized DNA is preferentially released in vitro both by non-stimulated or phytohemagglutinin-stimulated tonsil lymphocytes. Freshly isolated cells excrete DNA faster than phytohemagglutinin-stimulated ones. The acid-precipitable 3H-thymidine lost can be accounted for in the culture medium as labeled, double stranded DNA isolated on hydroxyapatite column.

摘要

新合成的DNA的主要部分在体外优先由未刺激的或经植物血凝素刺激的扁桃体淋巴细胞释放。新鲜分离的细胞比经植物血凝素刺激的细胞更快地排出DNA。在培养基中,可将损失的酸可沉淀的3H-胸腺嘧啶核苷解释为在羟基磷灰石柱上分离的标记双链DNA。

相似文献

4
DNA synthesis in tonsil lymphocytes. I. Changes in cell population during culture.
Biochem Med. 1976 Jun;15(3):246-53. doi: 10.1016/0006-2944(76)90055-7.
6
Fate of foreign DNA taken up by tonsillar lymphocytes.
Acta Biochim Biophys Acad Sci Hung. 1977;12(1):15-23.

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