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[对脑蛋白S - 100含量不同的两种近交系小鼠穿梭箱行为的遗传生化分析。II. 决定动物毛色及其学习能力的基因]

[Genetic-biochemical analysis of the shuttle box behavior of 2 inbred strains of mice differing in their brain protein S-100 content. II. Genes determining the animals coat color and their learning].

作者信息

Sviridov S M, Malup T K, Podoplelova M L

出版信息

Genetika. 1980;16(9):1652-9.

PMID:6935152
Abstract

The influence of genes, determining the coat colour in mice, on active avoidance conditioned reflex formation in a shuttle box was studied. Negative correlation was found to exist between theoretically calculated mean number of dominant genes determining the coat colour and the level of aviodance in a shuttle box. Among F2 hybrids and backcrosses the groups of mice characterized by different coat colour phenotype have similar concentration of neurospecific S-100 protein in cerebral cortex and hippocampus.

摘要

研究了决定小鼠毛色的基因对穿梭箱中主动回避条件反射形成的影响。发现决定毛色的理论计算显性基因平均数与穿梭箱中的回避水平之间存在负相关。在F2杂种和回交中,具有不同毛色表型的小鼠组在大脑皮层和海马体中神经特异性S-100蛋白的浓度相似。

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