Body B, Bilińska B
Folia Histochem Cytochem (Krakow). 1980;18(2):101-7.
Mouse males aged 2, 4 weeks, and 2 months were given PMS and HCG hormones, and testosterone in intramuscular injections. Leydig cells obtained from treated animals were histochemically investigated for the activity of delta 5, 3 beta-hydroxysteroid dehydrogenase). PMS caused no statistically significant changes in the activity of delta 5, 3 beta-OH-SDH in any of the investigated age groups of mice. However, in all tested groups treated with HCG the amount of cells having very strong enzyme activity increased. Testosterone injected into mice induced decrease of delta 5, 3 beta-OH-SDH activity. Both under the influence of HCG and testosterone differences between control group and experimental ones were statistically significant.
给2周龄、4周龄和2月龄的雄性小鼠肌肉注射促卵泡成熟素（PMS）、人绒毛膜促性腺激素（HCG）和睾酮。对经处理动物获取的睾丸间质细胞进行组织化学研究，检测其δ5,3β - 羟基类固醇脱氢酶的活性。PMS对任何所研究年龄组小鼠的δ5,3β - 羟基类固醇脱氢酶（δ5,3β - OH - SDH）活性均未引起统计学上的显著变化。然而，在所有用HCG处理的测试组中，具有很强酶活性的细胞数量增加。给小鼠注射睾酮导致δ5,3β - OH - SDH活性降低。在HCG和睾酮的影响下，对照组与实验组之间的差异具有统计学意义。
