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急性淋巴细胞白血病治疗的免疫学方法。

Immunological approach to the treatment of acute lymphoblastic leukemia.

作者信息

Bergolz V M, Kisljak N S, Eremeev V S, Rumjantzev A G, Akimova G V, Osipov S G

出版信息

Neoplasma. 1980;27(4):355-61.

PMID:6935532
Abstract

On the basis of experimental results an immunological method of acute lymphoblastic leukemia treatment by means of specific immunity regulation was designed. The administration of antibodies (immunoglobulins) with prednisolone to patients induced 100% remissions in a comparatively short time. None of the patients treated with immunoprednisolone therapy had neuroleukemia. The immunological findings indicate that the therapeutic effect depends on the "deblocking" action of the applied immune preparation.

摘要

根据实验结果,设计了一种通过特异性免疫调节治疗急性淋巴细胞白血病的免疫方法。给患者使用抗体(免疫球蛋白)加泼尼松龙,在相对较短的时间内诱导出100%的缓解率。接受免疫泼尼松龙治疗的患者均未发生神经白血病。免疫学研究结果表明,治疗效果取决于所应用免疫制剂的“去封闭”作用。

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