Goerig A C, Payne T F, del Rio C E
Oral Surg Oral Med Oral Pathol. 1980 Dec;50(6):557-62. doi: 10.1016/0030-4220(80)90440-5.
Sixty-nine rat mandibular molars were exposed surgically, and the pulpal response to ZOE with a purified form of eugenol versus ZOE with stock eugenol was investigated. Evaluation and analysis of the control and experimental specimens at 1, 3, 7 and 21 days indicated that there were no differences in the amount of inflammation observed between the two groups. Thus, it may be inferred from the results of this study that the impurities found in stock eugenol are not of clinical significance.
通过手术暴露69颗大鼠下颌磨牙，研究了纯化丁香酚的氧化锌丁香酚糊剂与含市售丁香酚的氧化锌丁香酚糊剂的牙髓反应。在第1、3、7和21天对对照和实验标本进行评估和分析，结果表明两组观察到的炎症量没有差异。因此，从本研究结果可以推断，市售丁香酚中发现的杂质不具有临床意义。
