与卡马西平相关的粒细胞缺乏症，以及恢复期间与抗淋巴细胞白血病抗血清的阳性反应。
Agranulocytosis associated with carbamazepine, and a positive reaction with anti-lymphoid leukaemia antiserum during recovery.
作者信息
Owens C W, Parker N E, Nunn P P, Davies J
出版信息
Postgrad Med J. 1980 Sep;56(659):665-8. doi: 10.1136/pgmj.56.659.665.
Abstract
Carbamazepine is a valuable drug in the treatment of trigeminal neuralgia and temporal lobe epilepsy. Rarely agranulocytosis has been described associated with its use but in this further non-fatal case a new finding of a positive reaction with anti-lymphoid leukaemia anti-serum was seen during the recovery phase. A brief review of 18 cases in the literature is provided and it is noted that 94% of reported cases are over the age of 45 years. The significance of the haematological finding is discussed.
摘要
卡马西平是治疗三叉神经痛和颞叶癫痫的一种重要药物。虽然很少有关于使用卡马西平后出现粒细胞缺乏症的报道，但在这例新的非致命病例中，在恢复阶段发现了与抗淋巴细胞白血病抗血清呈阳性反应的新情况。本文简要回顾了文献中报道的18例病例，并指出94%的报告病例年龄超过45岁。文中还讨论了血液学检查结果的意义。
相似文献
1
Agranulocytosis associated with carbamazepine, and a positive reaction with anti-lymphoid leukaemia antiserum during recovery.与卡马西平相关的粒细胞缺乏症，以及恢复期间与抗淋巴细胞白血病抗血清的阳性反应。
Postgrad Med J. 1980 Sep;56(659):665-8. doi: 10.1136/pgmj.56.659.665.
2
Fatal agranulocytosis developed in the course of carbamazepine therapy. A case report and review of the literature.卡马西平治疗过程中发生致命性粒细胞缺乏症。病例报告及文献综述。
Turk J Pediatr. 1995 Jan-Mar;37(1):73-7.
3
[The use of lithium salts in trigeminal neuralgia in prevention of neutropenia due to carbamazepine. Preliminary considerations].[锂盐在三叉神经痛中用于预防卡马西平所致中性粒细胞减少症。初步探讨]
Acta Neurol Quad (Napoli). 1979;39:149-52.
4
Fatal agranulocytosis in a chronic schizophrenic patient treated with carbamazepine.一名慢性精神分裂症患者在接受卡马西平治疗时发生致命性粒细胞缺乏症。
Am J Psychiatry. 1984 May;141(5):687-8. doi: 10.1176/ajp.141.5.687.
5
[Carbamazepine-induced agranulocytosis. Apropos of 2 cases].[卡马西平所致粒细胞缺乏症。附2例报告]
Recenti Prog Med. 1998 Oct;89(10):510-3.
6
[The cytological demonstration of immunoglobulin in stimulated lymphoid cells].[刺激淋巴细胞中免疫球蛋白的细胞学显示]
Acta Haematol. 1969;42(4):230-40. doi: 10.1159/000208783.
7
[Severe agranulocytosis induced by carbamazepine (Tegretol)].卡马西平（得理多）诱发的严重粒细胞缺乏症
Ann Fr Anesth Reanim. 1999 May;18(5):542-6. doi: 10.1016/s0750-7658(99)80129-4.
8
Agranulocytosis after administration of carbamazepine.服用卡马西平后出现粒细胞缺乏症。
Med J Aust. 1980 Jan 26;1(2):82-3. doi: 10.5694/j.1326-5377.1980.tb134642.x.
9
Unusual combination of erythroderma and agranulocytosis induced by carbamazepine.卡马西平诱发的红皮病与粒细胞缺乏症的罕见组合。
Therapie. 1998 Sep-Oct;53(5):513-4.
10
Hypogammaglobulinaemia with absent B lymphocytes and agranulocytosis after carbamazepine treatment.卡马西平治疗后出现低丙种球蛋白血症、B淋巴细胞缺如及粒细胞缺乏症。
J Neurol Neurosurg Psychiatry. 1996 Apr;60(4):459. doi: 10.1136/jnnp.60.4.459.
引用本文的文献
1
The Co-Existence of Agranulocytosis and Stevens-Johnson Syndrome (SJS) in Carbamazepine Therapy: A Case Report.卡马西平治疗中粒细胞缺乏症与史蒂文斯-约翰逊综合征（SJS）并存：一例报告
Cureus. 2022 Sep 7;14(9):e28917. doi: 10.7759/cureus.28917. eCollection 2022 Sep.
2
Anticonvulsant drugs and hematological disease.抗癫痫药物与血液系统疾病。
Neurol Sci. 2014 Jul;35(7):983-93. doi: 10.1007/s10072-014-1701-0. Epub 2014 Mar 12.
本文引用的文献
1
THE TREATMENT OF TRIGEMINAL NEURALGIA: PRELIMINARY EXPERIENCE WITH 'TEGRETOL'.三叉神经痛的治疗：使用“卡马西平”的初步经验
Practitioner. 1964 Jan;192:71-7.
2
TIC DOULOUREUX TREATED WITH NEW ANTICONVULSANT; EXPERIENCES WITH G 32883.新型抗惊厥药治疗三叉神经痛；G 32883的应用经验
Arch Neurol. 1963 Sep;9:285-90. doi: 10.1001/archneur.1963.00460090091009.
3
Detection and prevention of drug-induced blood dyscrasias.药物性血液系统疾病的检测与预防。
JAMA. 1962 Jul 14;181:114-9. doi: 10.1001/jama.1962.03050280044005e.
4
Acute lymphoblastic leukaemia associated antigen. IV. Expression on non-leukaemic 'lymphoid' cells.急性淋巴细胞白血病相关抗原。IV. 在非白血病“淋巴细胞”细胞上的表达。
Leuk Res. 1980;4(1):15-32. doi: 10.1016/0145-2126(80)90044-2.
5
Use of carbamazepine in epilepsy. Results in 87 patients.
JAMA. 1967 Apr 17;200(3):204-8.
6
Aplastic anaemia following the administration of tegretol.
Br J Clin Pract. 1965 Dec;19(12):699-702.
7
Tegretol in trigeminal neuralgia with special reference to hematopoietic side effects.卡马西平治疗三叉神经痛及其造血系统副作用的特别参考
Headache. 1969 Apr;9(1):58-63. doi: 10.1111/j.1526-4610.1969.hed0901058.x.
8
[Pancytopenia with fatal course during treatment with carbamazepine (Tegretol)].[卡马西平（得理多）治疗期间出现全血细胞减少并导致致命病程]
Ned Tijdschr Geneeskd. 1968 Nov 16;112(46):2089-90.
9
Clinical trials of tegretol in trigeminal neuralgia.卡马西平治疗三叉神经痛的临床试验。
Headache. 1969 Apr;9(1):77-82. doi: 10.1111/j.1526-4610.1969.hed0901077.x.
10
Carbamazepine in the treatment of neuralgia. Use of side effects.卡马西平治疗神经痛。副作用的应用。
Arch Neurol. 1968 Aug;19(2):129-36. doi: 10.1001/archneur.1968.00480020015001.
Zotero 插件