人类血小板单胺氧化酶与月经周期。

Human platelet monoamine oxidase and the menstrual cycle.

作者信息

Baron M, Levitt M, Perlman R

出版信息

Psychiatry Res. 1980 Dec;3(3):323-7. doi: 10.1016/0165-1781(80)90062-1.

Abstract

Endocrine factors are known to affect platelet monoamine oxidase (MAO) activity. To assess the role of sex steroid hormones in regulating MAO, blood samples for platelet MAO assay were obtained twice weekly from 12 women. Peak MAO activity occurred during the ovulatory interval and a nadir occurred in the postovulatory phase, 5 to 6 days later. A 17% mean effect of menstrual variation from peak to nadir was noted. The implications for MAO studies in psychiatric research are discussed.

摘要

已知内分泌因素会影响血小板单胺氧化酶（MAO）的活性。为评估性类固醇激素在调节MAO中的作用，每周两次从12名女性身上采集用于血小板MAO检测的血样。MAO活性峰值出现在排卵期，最低点出现在排卵后5至6天的排卵后期。观察到月经周期从峰值到最低点的平均变化幅度为17%。文中讨论了其在精神病学研究中对MAO研究的意义。