Slobodniuk R, Naraqi S
P N G Med J. 1980 Sep;23(3):111-6.
A retrospective review of cryptococcal meningitis in Papua New Guinea adults showed that the condition is at least as common as tuberculous meningitis. The majority of the patients were young and all were previously healthy. A mortality rate of more than 50% was observed despite amphotericin B therapy. Cryptococcal aetiology should be suspected and looked for in every patient with chronic meningitis in Papua New Guinea. Examining the cerebrospinal fluid for cryptococcal antigen is of value when Indian ink smear and culture are negative.
对巴布亚新几内亚成年人隐球菌性脑膜炎的一项回顾性研究表明，该病至少与结核性脑膜炎一样常见。大多数患者较为年轻，且此前均身体健康。尽管采用了两性霉素B治疗，但仍观察到死亡率超过50%。在巴布亚新几内亚，对于每一位患有慢性脑膜炎的患者，都应怀疑并寻找隐球菌病因。当印度墨汁涂片和培养结果为阴性时，检测脑脊液中的隐球菌抗原具有重要价值。
