Treatment of tetanus by lumbar intrathecal tetanus-antitoxin.

The use of human tetanus antitoxin by lumbar intrathecal injection for the treatment of tetanus in five consecutive cases is reported. The intrathecal administration of human tetanus antitoxin as part of treatment appears to be the most effective treatment of tetanus and should be given as soon as the diagnosis of tetanus is established. The dose of antitoxin does not relate with the rapid improvement of muscle spasm.