Gidley-Baird A A
J Reprod Fertil Suppl. 1981;29:97-109.
Progesterone and oestrogen are required for implantation in the mouse and rat. In both animals prolactin and LH stimulate ovarian progesterone production oestrogen is stimulated by FSH in the mouse but both LH and FSH appear to be required in the rat. There is no evidence that preimplantation embryonic gonadotrophins, if they exist in these species, are involved in the initiation of implantation. The delay of implantation in suckling mice and rats is due to a lack of oestrogenic stimulus. This is caused by an inhibition of FSH release from the pituitary gland. The inhibition of FSH release appears to be caused by lack of a competent hypothalamic releasing factor. High circulating levels of prolactin and/or LH and/or progesterone do not seem to be responsible for the FSH inhibition during suckling-induced delayed implantation. Increased or decreased prolactin release does not affect FSH release during early pregnancy in the mouse.
在小鼠和大鼠体内，着床需要孕酮和雌激素。在这两种动物中，催乳素和促黄体生成素刺激卵巢产生孕酮，在小鼠中雌激素由促卵泡生成素刺激产生，但在大鼠中促黄体生成素和促卵泡生成素似乎都有必要。没有证据表明，在这些物种中如果存在着床前胚胎促性腺激素，它们会参与着床的起始过程。哺乳小鼠和大鼠的着床延迟是由于缺乏雌激素刺激。这是由垂体促卵泡生成素释放受抑制引起的。促卵泡生成素释放受抑制似乎是由缺乏有效的下丘脑释放因子导致的。高循环水平的催乳素和/或促黄体生成素和/或孕酮似乎并不负责哺乳诱导的着床延迟期间促卵泡生成素的抑制。催乳素释放增加或减少并不影响小鼠妊娠早期的促卵泡生成素释放。
