免疫抑制治疗期间的急性白血病。1例报告（作者译）
[Acute leukaemia during immunosuppressive treatment. One case (author's transl)].
作者信息
Blanc A P, Gastaut J A, Sébahoun G, Dalivoust P, Murisasco A, Carcassonne Y
出版信息
Nouv Presse Med. 1981 May 9;10(21):1717-9.
A 55-year-old man was treated during 22 months with chlorambucil (total dose : 4 218 g) for glomerulonephritis. Towards the end of the treatment, he developed acute myelomonocytic leukaemia and died of this complication. The authors underline the oncogenetic dangers of the association dysimmune disease/immunosuppressive treatment and draw attention to the almost regular preleukaemic phase with its well-known cytological, biochemical, immunological, cytogenetic and evolutive criteria.
一名55岁男性因肾小球肾炎接受了22个月的苯丁酸氮芥治疗（总剂量：4218克）。治疗快结束时，他患上了急性粒单核细胞白血病，并死于该并发症。作者强调了免疫失调疾病/免疫抑制治疗联合使用的致癌风险，并提请注意几乎都会出现的白血病前期，以及其众所周知的细胞学、生化、免疫学、细胞遗传学和病情发展标准。
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