Bucher U, Tschopp L
Schweiz Med Wochenschr. 1981 Mar 28;111(13):438-43.
Whenever leukaemia is suspected the diagnosis should be firmly established or excluded without delay. Clinical examination, blood counts (including platelet count) and a blood smear usually serve to diagnose or rule out chronic leukaemias. Bone marrow examination is necessary for the diagnosis of acute leukaemias. The value of additional tests, some of which are highly sophisticated, is not yet established. Chemotherapy of chronic leukaemias remains symptomatic. Various combinations of cytostatic drugs are used for treatment of acute leukaemias. Complete remissions are mostly achieved after transient bone marrow aplasia; this aplastic phase must be overcome by supportive measures. Although long survival is still exceptional in the adult, cure of the leukaemias appears to be theoretically possible. This view is supported by the preliminary results of bone marrow transplantation.
一旦怀疑患有白血病,应立即明确诊断或排除诊断。临床检查、血细胞计数(包括血小板计数)和血涂片通常用于诊断或排除慢性白血病。急性白血病的诊断需要进行骨髓检查。一些高度复杂的额外检查的价值尚未确定。慢性白血病的化疗仍以对症治疗为主。各种细胞毒性药物组合用于治疗急性白血病。短暂的骨髓抑制后大多可实现完全缓解;必须通过支持措施度过这个再生障碍期。尽管成人长期存活仍属罕见,但白血病在理论上似乎有可能治愈。骨髓移植的初步结果支持了这一观点。