Forfang K, Rostad H, Sørland S
Acta Med Scand Suppl. 1981;645:15-22. doi: 10.1111/j.0954-6820.1981.tb02596.x.
Twohundred and eighteen patients aged 13 years or more at operation for coarctation of the aorta were selected for a long-term postoperative follow-up study. The mean age of operation was 25,3 years, range 13 to 62 years, and the mean follow-up period was 13 years, range 2 to 28 years. The surgical mortality rate was 1.4%, all 3 patients being in their fourth decade. There were 35 late deaths (16,3%), 26 having cardiovascular disease as the causation; 3 patients developed a dissecting aneurysm of the ascending aorta, and 11 died suddenly of unknown cause. Persisting hypertension was found in approximately one third of the patients. A highly significant correlation was demonstrated between the systolic blood pressures before and after surgery. Aortic valve disease occurred in 31 patients (14,2%). Coarctation of the aorta should be operated on in childhood, and a close postoperative long-term follow-up in all patients is recommended.
选取了218例在主动脉缩窄手术时年龄在13岁及以上的患者进行术后长期随访研究。手术的平均年龄为25.3岁,范围为13至62岁,平均随访期为13年,范围为2至28年。手术死亡率为1.4%,所有3例患者均为40多岁。有35例晚期死亡(16.3%),其中26例的死因是心血管疾病;3例发生升主动脉夹层动脉瘤,11例原因不明突然死亡。约三分之一的患者存在持续性高血压。术前和术后收缩压之间显示出高度显著的相关性。31例患者(14.2%)发生主动脉瓣疾病。主动脉缩窄应在儿童期进行手术,建议对所有患者进行密切的术后长期随访。