Shapiro P A, Kokich V G, Hohl T H, Loe C
Am J Orthod. 1981 May;79(5):492-9. doi: 10.1016/s0002-9416(81)90461-9.
Le Fort I osteotomies were performed on three juvenile Macaca nemestrina monkeys with midface deficiencies from prior extraoral traction. The maxillas of these monkeys were moved anteriorly an amount necessary to achieve about 8 mm. of horizontal overjet. Interosseous wires were used to stabilize the segments; the animals were not placed in intermaxillary fixation. Craniofacial growth in the three experimental monkeys and in three control monkeys was monitored for 2 years with serial cephalometric radiographs. Compared to the controls, the maxillas of the experimental animals demonstrated less anterior growth, and this was manifested clinically in anterior dental cross-bite relationships. Histologic examination of the circummaxillary sutural complex revealed normal morphology. It is concluded, therefore, that early Le Fort I osteotomies significantly affect subsequent maxillary growth in monkeys and that this effect probably is due to formation of scar tissue.
对三只因先前口外牵引导致面中部发育不全的幼年豚尾猴进行了勒福Ⅰ型截骨术。这些猴子的上颌骨向前移动至实现约8毫米水平覆盖所需的量。使用骨间钢丝稳定骨段;动物未进行颌间固定。用连续头颅侧位X线片对三只实验猴和三只对照猴的颅面生长进行了2年监测。与对照组相比,实验动物的上颌骨向前生长较少,这在临床上表现为前牙反合关系。上颌周围缝合复合体的组织学检查显示形态正常。因此得出结论,早期勒福Ⅰ型截骨术显著影响猴子随后的上颌生长,且这种影响可能是由于瘢痕组织形成。