Leukemic optic nerve infiltration 17 months after cessation of therapy.

A patient with leukemic optic nerve infiltration is presented. It occurred as an isolated manifestation of leukemia 17 months after therapy for acute lymphocytic leukemia was discontinued. Therapy with prednisone and vincristine was effective in reducing optic nerve infiltration in a short period of time. This observation leads to the conclusion that the optic nerve does not belong to the pharmacological sanctuary.