Nique T A, Bennett C R
Oral Surg Oral Med Oral Pathol. 1981 May;51(5):468-70. doi: 10.1016/0030-4220(81)90002-5.
Total brainstem anesthesia with respiratory arrest followed extraoral trigeminal V2-V3 diagnostic nerve blocks for trigeminal neuralgia using a combination of 0.25 percent Bupivacaine, Sarapin, and triamcinolone. While an untoward reaction to either the Sarapin or triamcinolone cannot be ruled out, the most probable cause for this problem was the inadvertent intrathecal injection of Bupivacaine since the reaction can be explained on the basis of a local anesthetic effect. No such effect has been attributed to either of the other components of the mixture. Proper monitoring and prompt attention permitted attenuation of this potentially life-threatening complication.
在使用0.25%布比卡因、沙巴因和曲安奈德联合进行三叉神经痛的口外三叉神经V2 - V3诊断性神经阻滞之后，出现了伴有呼吸骤停的全脑干麻醉。虽然不能排除对沙巴因或曲安奈德的不良反应，但该问题最可能的原因是布比卡因意外鞘内注射，因为这种反应可以基于局部麻醉作用来解释。混合物的其他成分均未被认为有此类作用。适当的监测和及时的处理使得这一潜在的危及生命的并发症得到了缓解。
