Vohra J, Hamer A, Mond H, Sloman G, Hunt D
Aust N Z J Med. 1981 Feb;11(1):27-34. doi: 10.1111/j.1445-5994.1981.tb03732.x.
Seven patients with recurrent paroxysmal supraventricular tachycardia (PSVT) resistant to standard drug therapy were treated with patient initiated implantable pacemakers. All patients had required frequent hospital admissions and cardioversions prior to pacemaker implantation. Two patients had Wolff-Parkinson-White (WPW) syndrome on their surface ECGs and five patients had no ECG evidence of preexcitation. All patients had detailed electrophysiological studies. Three patients had junctional tachycardia, one patients had reciprocating atrial tachycardia and in three, including one with normal surface ECG, retrogradely conducting accessory atrio-ventricular connections (AAVC) formed a part of the tachycardia circuit. Initiation and termination of tachycardia were re-checked at subsequent studies. On the basis of these studies, two patients with WPW syndrome had right ventricular endocardial leads and custom-built, magnet actuated pacemakers capable of delivering right ventricular coupled stimuli at fixed, present intervals of 200 and 400 ms. Both these pacemakers provided inconsistent reversions and proved unsatisfactory. In the remaining five patients, a unipolar tined J-shaped right atrial (RA) lead (Medtronic 6991) and a radiofrequency (RF) receiver (Medtronic 5998T) were implanted and enabled patients to overdrive ranged from 14 to 20 months. Several episodes of PSVT have been consistently reverted and none have required hospitalisation or cardio-version. Two patients had transient atrial fibrillation following the application of RF pacemaker. Three have required no antiarrhythmic drugs and in two the drug therapy has been greatly reduced and simplified. The Medtronic 6991 lead provided satisfactory RA stimulation without dislodgement. In carefully selected patients with PSVT, RF pacemakers provide a useful mode of treatment.
七例复发性阵发性室上性心动过速(PSVT)且对标准药物治疗耐药的患者接受了患者自行启动的植入式起搏器治疗。所有患者在起搏器植入前均需频繁住院及进行心脏复律。两名患者体表心电图显示有预激综合征(WPW),五名患者心电图无预激迹象。所有患者均进行了详细的电生理研究。三名患者为交界性心动过速,一名患者为折返性房性心动过速,三名患者(包括一名体表心电图正常者)的心动过速环路中包含逆向传导的房室旁道(AAVC)。在随后的研究中对心动过速的诱发和终止情况进行了复查。基于这些研究,两名患有WPW综合征的患者植入了右心室心内膜导线以及定制的、可由磁铁驱动的起搏器,该起搏器能够以200和400毫秒的固定当前间期发放右心室耦合刺激。这两种起搏器均提供了不一致的复律效果,结果并不理想。在其余五名患者中,植入了单极带倒刺J形右心房(RA)导线(美敦力6991)和射频(RF)接收器(美敦力5998T),患者能够超速抑制心动过速达14至20个月。多次PSVT发作均持续被复律,无一例需要住院或进行心脏复律。两名患者在应用射频起搏器后出现短暂房颤。三名患者无需使用抗心律失常药物,两名患者的药物治疗已大幅减少并简化。美敦力6991导线提供了满意的右心房刺激且未发生移位。在精心挑选的PSVT患者中,射频起搏器提供了一种有效的治疗方式。