Cochran M
Aust N Z J Med. 1981;11(Suppl 1):33-7.
In advanced chronic renal failure hypocalcaemia can be due to a combination of factors. These include decreased delivery of calcium into the plasma and increased renal tubular leakage of calcium. The secondary hyperparathyroidism that follows the hypocalcaemia leads to osteosclerosis, probably by movement of cortical mineral into trabecular bone. In the dialysis population, an atypical and readily identifiable form of osteomalacia sometimes occurs and is probably secondary to a water-borne toxin.
在晚期慢性肾衰竭中，低钙血症可能是多种因素共同作用的结果。这些因素包括进入血浆的钙输送减少以及肾小管钙漏出增加。低钙血症继发的继发性甲状旁腺功能亢进可能通过皮质矿物质向小梁骨的移动导致骨硬化。在透析人群中，有时会出现一种非典型且易于识别的骨软化形式，可能继发于一种经水传播的毒素。
