Tokudome S, Kono S, Ikeda M, Kuratsune M, Kumamaru S
J Natl Cancer Inst. 1981 Aug;67(2):285-9.
A follow-up study was done on the mortality from 1956 to 1975 among 2,383 Japanese patients with leprosy who were admitted to a leprosarium in Japan. The leprosy was classified into two types: lepromatous and tuberculoid. Irrespective of the type of leprosy or the sex of leprosy patient, mortalities were increased from tuberculosis, pneumonia and bronchitis, nephritis and nephrosis, and from total causes. The suicide rate was high among female patients. Deaths from total malignant neoplasms were higher than expected among patients with lepromatous leprosy for both sexes (49 observed vs. 44.02 expected), whereas they were lower than expected among patients with tuberculoid leprosy (35 observed vs. 36.83 expected); however, the differences were not statistically significant. Mortalities from cancers of the cervix and the esophagus among females with lepromatous leprosy were significantly higher. The risk of lymphoreticular cancers was not increased.
对入住日本一家麻风病疗养院的2383名日本麻风病患者在1956年至1975年间的死亡率进行了一项随访研究。麻风病分为两型：瘤型和结核样型。无论麻风病类型或麻风病患者性别如何，结核病、肺炎和支气管炎、肾炎和肾病以及所有病因导致的死亡率均有所上升。女性患者的自杀率较高。两性瘤型麻风病患者的全部恶性肿瘤死亡人数均高于预期（观察到49例，预期44.02例），而结核样型麻风病患者的全部恶性肿瘤死亡人数低于预期（观察到35例，预期36.83例）；然而，差异无统计学意义。瘤型麻风病女性患者的宫颈癌和食管癌死亡率显著更高。淋巴网状系统癌症的风险未增加。
