Bruder G, Sutton S, Berger-Gross P, Quitkin F, Davies S
Psychiatry Res. 1981 Jun;4(3):253-66. doi: 10.1016/0165-1781(81)90027-5.
The intensity needed to detect dichotic click stimuli was measured in 14 bipolar depressed patients, 19 unipolar depressed patients, and 15 normal controls. The results replicated, in unmedicated bipolar depressed patients, an earlier finding of reversed lateral asymmetry in medicated affective psychotic patients. Two new findings concern the relation of lateral asymmetry patterns to diagnostic subtypes of the Research Diagnostic Criteria and symptom ratings on the Schedule for Affective Disorders and Schizophrenia. First, patients with bipolar disorders (history of mania or hypomania) were more likely than patients with unipolar disorders to display reversed lateral asymmetry. Second, greater severity of depressive or endogenous symptoms was associated with less lateral asymmetry.
在14名双相情感障碍抑郁症患者、19名单相情感障碍抑郁症患者和15名正常对照者中测量了检测双耳分听滴答声刺激所需的强度。结果在未用药的双相情感障碍抑郁症患者中重现了之前在用药的情感性精神病患者中发现的外侧不对称反转现象。有两个新发现涉及外侧不对称模式与研究诊断标准的诊断亚型以及情感障碍和精神分裂症评定量表上的症状评分之间的关系。首先，双相情感障碍（有躁狂或轻躁狂病史）患者比单相情感障碍患者更有可能表现出外侧不对称反转。其次，抑郁或内源性症状的严重程度越高，外侧不对称程度越低。
