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普鲁卡因胺引起的可逆性严重贫血和粒细胞减少症。病例报告。

Reversible severe anaemia and granulocytopenia caused by procainamide. A case report.

作者信息

van Beek R J, Bieger R, den Ottolander G J

出版信息

Scand J Haematol. 1978 Aug;21(2):150-2. doi: 10.1111/j.1600-0609.1978.tb02505.x.

DOI:10.1111/j.1600-0609.1978.tb02505.x
PMID:694426
Abstract

A 64-year-old male developed severe anaemia during procainamide therapy. At the same time granulocytopenia was found. Discontinuation of procainamide led to complete recovery. Severe anaemia due to the use of procainamide is not well known. The available data indicate a maturation block of the erythropoiesis as the possible cause of the anaemia, perhaps in combination with an autoimmune haemolysis.

摘要

一名64岁男性在普鲁卡因胺治疗期间出现严重贫血。同时发现粒细胞减少。停用普鲁卡因胺后完全康复。使用普鲁卡因胺导致严重贫血的情况并不为人熟知。现有数据表明红细胞生成的成熟障碍可能是贫血的原因,或许还伴有自身免疫性溶血。

相似文献

1
Reversible severe anaemia and granulocytopenia caused by procainamide. A case report.普鲁卡因胺引起的可逆性严重贫血和粒细胞减少症。病例报告。
Scand J Haematol. 1978 Aug;21(2):150-2. doi: 10.1111/j.1600-0609.1978.tb02505.x.
2
Sustained-release procainamide-induced reversible granulocytopenia after myocardial infarction.心肌梗死后缓释普鲁卡因胺诱发可逆性粒细胞减少症。
Jpn Heart J. 1995 Jul;36(4):483-7. doi: 10.1536/ihj.36.483.
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Severe transient pancytopenia associated with procainamide ingestion.
JAMA. 1976 Nov 29;236(22):2520-1.
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Agranulocytosis associated with procainamide therapy--report of a case.与普鲁卡因胺治疗相关的粒细胞缺乏症——一例报告。
Am J Hosp Pharm. 1977 Dec;34(12):1362-5.
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Procainamide-induced agranulocytosis and thrombocytopenia.
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Agranulocytosis secondary to extended-release procainamide: a case report and review of the literature. A case of agranulocytosis caused by procainamide in a patient who had undergone open-heart surgery.
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Agranulocytosis caused by procainamide.普鲁卡因胺引起的粒细胞缺乏症。
Scott Med J. 1972 May;17(5):165-8. doi: 10.1177/003693307201700501.
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Procainamide-induced agranulocytosis: report of two cases and review.
J Kans Med Soc. 1980 Jan;81(1):18-24.
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[Agranulocytosis caused by procainamide (Pronestyl)].[普鲁卡因胺(普罗奈斯地)引起的粒细胞缺乏症]
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Agranulocytosis in a 12-year-old girl treated with procainamide.一名接受普鲁卡因胺治疗的12岁女孩发生粒细胞缺乏症。
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Severe neutropenia consequent to sustained-release procainamide.缓释普鲁卡因胺所致的严重中性粒细胞减少症。
Tex Heart Inst J. 1983 Mar;10(1):85-7.