普鲁卡因胺引起的可逆性严重贫血和粒细胞减少症。病例报告。
Reversible severe anaemia and granulocytopenia caused by procainamide. A case report.
作者信息
van Beek R J, Bieger R, den Ottolander G J
出版信息
Scand J Haematol. 1978 Aug;21(2):150-2. doi: 10.1111/j.1600-0609.1978.tb02505.x.
Abstract
A 64-year-old male developed severe anaemia during procainamide therapy. At the same time granulocytopenia was found. Discontinuation of procainamide led to complete recovery. Severe anaemia due to the use of procainamide is not well known. The available data indicate a maturation block of the erythropoiesis as the possible cause of the anaemia, perhaps in combination with an autoimmune haemolysis.
摘要
一名64岁男性在普鲁卡因胺治疗期间出现严重贫血。同时发现粒细胞减少。停用普鲁卡因胺后完全康复。使用普鲁卡因胺导致严重贫血的情况并不为人熟知。现有数据表明红细胞生成的成熟障碍可能是贫血的原因，或许还伴有自身免疫性溶血。
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