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分化诱导型与未诱导型弗瑞德红白血病细胞核蛋白的比较。

Comparison of nuclear proteins of differentiation-induced and uninduced Friend erythroleukemia cells.

作者信息

Morioka K, Tanaka K, Ono T

出版信息

J Biochem. 1981 May;89(5):1633-8. doi: 10.1093/oxfordjournals.jbchem.a133358.

Abstract

Nuclear non-histone protein content decreased to about 50% during the course of differentiation of Friend cells (Morioka, K., Tanaka K, & Ono, T. (1980) J. Biochem. 88 517-524). Judging from the patterns of Coomassie blue staining after SDS-polyacrylamide gel electrophoresis, the contents of non-histone proteins generally decreased, except for a few proteins such as IP25, while no marked change was observed in histones during differentiation.

摘要

在弗瑞德细胞分化过程中,核内非组蛋白含量降至约50%(森冈 克、田中 克、小野 敏,1980年,《生物化学杂志》第88卷,第517 - 524页)。从十二烷基硫酸钠 - 聚丙烯酰胺凝胶电泳后的考马斯亮蓝染色模式判断,除了如IP25等少数蛋白质外,非组蛋白的含量总体上有所下降,而在分化过程中组蛋白未观察到明显变化。

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