Sander S, Nissen-Meyer R, Aakvaag A
Scand J Urol Nephrol. 1978;12(2):119-21. doi: 10.3109/00365597809179977.
Depostat treatment was found to reduce plasma testosterone and to have a gonadotrophin suppressive effect in males. In our study the clinical effect on prostatic cancer was, however, disappointing when compared to the well established effect of orchiectomy. The therapeutic failure of Depostat might be related to the incomplete suppression of plasma testosterone compared to that observed after orchiectomy.
已发现去势治疗可降低男性血浆睾酮水平，并对促性腺激素有抑制作用。然而，在我们的研究中，与已确立的睾丸切除术的效果相比，去势治疗对前列腺癌的临床效果令人失望。与睾丸切除术后观察到的情况相比，去势治疗的治疗失败可能与血浆睾酮抑制不完全有关。
