Grillon G L, Lally E T
J Oral Surg. 1981 Oct;39(10):747-53.
Necrotizing sialometaplasia is a benign, ulcerative, inflammatory process of the minor salivary glands, primarily found in the hard palate. It is often mistaken clinically and histologically for a malignant tumor (that is, mucoepidermoid or squamous cell carcinoma). The lesion heals spontaneously in six to 12 weeks. It occurs primarily in persons between the ages of 40 and 60 and has been reported more frequently in men than women. In necrotizing sialometaplasia the squamous metaplasia and tissue necrosis is confined to the existing ductal and lobular pattern of the salivary glands, a unique characteristic that aids in diagnosis. Five additional cases are presented.
坏死性涎腺化生是一种主要发生于硬腭的小涎腺的良性、溃疡性炎症过程。临床上和组织学上它常被误诊为恶性肿瘤（即黏液表皮样癌或鳞状细胞癌）。该病变在6至12周内可自愈。它主要发生在40至60岁的人群中，据报道男性比女性更常见。在坏死性涎腺化生中，鳞状化生和组织坏死局限于涎腺现有的导管和小叶结构，这一独特特征有助于诊断。本文还介绍了另外5例病例。
