Kutty C P, Remeniuk E, Varkey B
Acta Cytol. 1981 Jul-Aug;25(4):412-6.
Malignant-appearing mesothelial cells were noted in an amylase-rich pleural effusion caused by pancreatitis in the absence of any neoplastic disease. Such changes in the mesothelial cells are believed to be the result of intense irritation of the serosal surfaces by the pancreatic enzymes. Review of the literature showed a likelihood of false-positive cytologic diagnosis of 0.44% for pleural effusions and 0.91% for all serous effusions. Because of the potential for serious error in patient management based on a false-positive cytology, it is important to recognize the conditions that may be responsible for it.
在由胰腺炎引起的富含淀粉酶的胸腔积液中发现了形态可疑的间皮细胞，而患者并无任何肿瘤性疾病。间皮细胞的这种变化被认为是胰腺酶对浆膜表面强烈刺激的结果。文献回顾显示，胸腔积液的细胞学假阳性诊断可能性为0.44%，所有浆液性积液的为0.91%。由于基于假阳性细胞学结果可能在患者管理中导致严重错误，因此识别可能导致假阳性的情况很重要。
