Lahiri T, Chowdhury J R
Acta Cytol. 1981 Sep-Oct;25(5):572-7.
A comprehensive study was made of the patterns of lipid granules in vaginal cells exfoliated during different hormonal states as well as under neoplastic conditions. The influence of in vitro incubation with estrogen and progesterone on the lipid patterns in cells exfoliated from normal and cancerous cervices was also investigated. The results clearly indicated the influence of sex hormones on the size and distribution of the lipid granules. While estrogen increased the fine lipid granules, as evident during the estrogenic phase of the menstrual cycle, progesterone influenced the coarse granules, which increased during the progestational phase and pregnancy. Similar responses were observed in the in vitro studies. The significance of the fine and coarse granules in different conditions is discussed in light of both the alteration of the metabolic process governing the synthesis of these components and the conversion of fine granules to coarse granules under such conditions.
对不同激素状态下以及肿瘤状态下脱落的阴道细胞中脂质颗粒的模式进行了全面研究。还研究了雌激素和孕激素体外孵育对正常和癌性宫颈脱落细胞脂质模式的影响。结果清楚地表明了性激素对脂质颗粒大小和分布的影响。雌激素增加了细脂质颗粒，如在月经周期的雌激素期所见，孕激素则影响粗颗粒，粗颗粒在孕激素期和孕期增加。体外研究中也观察到了类似的反应。根据控制这些成分合成的代谢过程的改变以及在此类条件下细颗粒向粗颗粒的转化，讨论了不同条件下细颗粒和粗颗粒的意义。
