Bukhari A R
Bull Tokyo Med Dent Univ. 1981 Sep;28(3):77-86.
A theoretical model for computer simulation has been introduced to predict the unipolar epicardial potentials corresponding to the different angles of propagation of the excitation wavefront. The simulated waveforms were compared with those observed in the animal experiments. In these experiments three unipolar epicardial potentials and one intramural potential were recorded using a thumbtack electrode with and without bipolar epicardial pacing. The direction of the propagation of the excitation was determined from the arrival time of the recorded waveforms. There was a close correspondence between the observed and the simulated waveforms. Furthermore, it was attempted to establish a quantitative relationship between the unipolar potential waveshape and the angle of propagation theta of the excitation. The difference between the positive and the negative peak normalized by the peak-to-peak height was used to define the change in the waveshape. A distinct relation was found to exist between the normalized difference R and the angle theta for the simulated potentials. There was a good correlation (r = 0.96 for n = 85) between angle theta 1 calculated from the arrival times and theta 2 determined from R, which suggest that the angle theta can be estimated from the unipolar epicardial potentials alone, without using any intramural electrode.
已引入一种用于计算机模拟的理论模型，以预测与兴奋波前不同传播角度相对应的单极心外膜电位。将模拟波形与在动物实验中观察到的波形进行比较。在这些实验中，使用图钉电极在有和没有双极心外膜起搏的情况下记录了三个单极心外膜电位和一个心内电位。根据记录波形的到达时间确定兴奋的传播方向。观察到的波形与模拟波形之间存在密切对应关系。此外，试图建立单极电位波形与兴奋传播角度θ之间的定量关系。用峰峰值高度归一化后的正峰与负峰之间的差值来定义波形的变化。对于模拟电位，发现归一化差值R与角度θ之间存在明显关系。根据到达时间计算出的角度θ1与根据R确定的角度θ2之间存在良好的相关性（n = 85时，r = 0.96），这表明仅通过单极心外膜电位就可以估计角度θ，而无需使用任何心内电极。
