Hornych A
Nephrologie. 1980;1(3):113-6.
Diagnostic value of plasma and urinary prostaglandins E2 and F2 alpha measurements was compared in 5 patients with Bartter's syndrome and 5 patients with pseudo-Bartter's syndrome. Bartter's syndrome is characterised by constant simultaneous increase of plasma and urinary PGE2; this hypersecretion is insufficiently suppressed by indomethacin treatment. Pseudo-Bartter's syndrome is characterised by normal urinary PGE2 excretion which is considerably decreased by indomethacin treatment at the same dose. The measurement of plasma and urinary prostaglandins helps to distinguish the Bartter's syndrome from pseudo-Bartter's syndrome.
对5例巴特综合征患者和5例假性巴特综合征患者血浆及尿液中前列腺素E2和F2α的检测诊断价值进行了比较。巴特综合征的特征是血浆和尿液中PGE2持续同时升高；吲哚美辛治疗不能充分抑制这种高分泌。假性巴特综合征的特征是尿PGE2排泄正常，相同剂量的吲哚美辛治疗可使其显著降低。血浆和尿液中前列腺素的检测有助于区分巴特综合征和假性巴特综合征。
