Dygin V P, Kotsiubinskiĭ N N, Siubaeva N I, Likhachev L V
Vopr Onkol. 1981;27(10):77-81.
The paper presents an evaluation of 1.236 cases of different forms of leukemia. Malignant tumors of different localizations were identified in 21 cases (1.7%). Neoplasms were most frequently associated with chronic lymphoid leukemia (4%), followed by osteomyelosclerosis (1.3%), chronic myeloleukemia (1%), polycythemia (0.9%) and acute leukemia (0.44%). A case of chronic myeloleukemia with concomitant myelosarcoma, thyroid cancer, malignant tumor of kidney and cortical adenoma is presented. The role of immunological disorders and cytostatic therapy in the genesis of "secondary" tumor are discussed.
本文对1236例不同类型白血病进行了评估。21例（1.7%）发现有不同部位的恶性肿瘤。肿瘤最常与慢性淋巴细胞白血病相关（4%），其次是骨髓硬化症（1.3%）、慢性粒细胞白血病（1%）、红细胞增多症（0.9%）和急性白血病（0.44%）。文中介绍了1例伴有骨髓肉瘤、甲状腺癌、肾恶性肿瘤和皮质腺瘤的慢性粒细胞白血病病例。讨论了免疫紊乱和细胞抑制疗法在“继发性”肿瘤发生中的作用。
