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肢端雀斑样痣型黑色素瘤或四肢哈钦森黑色素雀斑。病例报告。

Acral lentiginous melanoma or Hutchinson's melanotic freckle of the extremities. A case report.

作者信息

Rippey J J, Lewin J R

出版信息

S Afr Med J. 1978 Jun 24;53(26):1076-7.

PMID:694684
Abstract

An additional category of malignant melanoma of the skin, i.e. acral lentiginous melanoma, has been proposed by some authors. The lesion occurs on the extremities, particularly the soles of the feet, the palms of the hands and the digits, but otherwise has the clinical, histological and prognostic features of Hutchinson's melanotic freckle with melanoma. A case conforming to the description of Hutchinson's melanotic freckle of the sole of the foot occurring in a White patient is described. Reference is also made to previous studies of malignant melanoma of the extremities in Black patients. In 15% of these the histogenetic pattern of Hutchinson's melanotic freckle could be observed in the epidermis, adjacent to the invasive melanoma. This pattern was associated with a very much better prognosis than was the superficial spreading or nodular type. The advisability of introducing a new category of acral lentiginous melanoma is therefore questioned.

摘要

一些作者提出了皮肤恶性黑色素瘤的另一类别,即肢端雀斑样痣黑色素瘤。该病变发生在四肢,特别是足底、手掌和手指,但在其他方面具有哈钦森黑素雀斑伴黑色素瘤的临床、组织学和预后特征。本文描述了1例符合足底哈钦森黑素雀斑描述的白人患者病例。同时也提及了之前对黑人患者四肢恶性黑色素瘤的研究。在其中15%的病例中,可在侵袭性黑色素瘤附近的表皮中观察到哈钦森黑素雀斑的组织发生模式。与浅表扩散型或结节型相比,这种模式的预后要好得多。因此,引入肢端雀斑样痣黑色素瘤这一新类别的合理性受到质疑。

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