Bradley G W, Sterling G M
Thorax. 1978 Aug;33(4):464-7. doi: 10.1136/thx.33.4.464.
In two patients with extensive pulmonary tuberculosis who developed hypercalcaemia and hypokalaemia the hypercalcaemia appeared related to the use of small doses of vitamin D, which suggested patients with tuberculosis were hypersensitive to vitamin D. They were thus similar to patients with sarcoidosis, and it is interesting that the Kveim test result was positive in both cases. The hypercalcaemia was quickly suppressed with steroids. Hyperparathyroidism, thyrotoxicosis, Addison's disease, and multiple myeloma were excluded on clinical grounds and by the appropriate tests. The hypokalaemia was associated with increased renal excretion of potassium, and was probably due to distal tubular damage from hypercalcaemia.
在两名患有广泛肺结核并出现高钙血症和低钾血症的患者中，高钙血症似乎与小剂量维生素D的使用有关，这表明肺结核患者对维生素D过敏。因此，他们与结节病患者相似，有趣的是，这两例患者的克维姆试验结果均为阳性。高钙血症通过类固醇迅速得到抑制。基于临床依据并通过适当检查排除了甲状旁腺功能亢进、甲状腺毒症、艾迪生病和多发性骨髓瘤。低钾血症与肾脏钾排泄增加有关，可能是由于高钙血症导致远端肾小管损伤所致。
