肺气肿中的膈肌与体重
Diaphragm and body weight in emphysema.
作者信息
Thurlbeck W M
出版信息
Thorax. 1978 Aug;33(4):483-7. doi: 10.1136/thx.33.4.483.
The weight of the diaphragm has been investigated in 103 male patients and 81 female patients, and the relationship between body weight and emphysema has been assessed in 662 male and 431 female patients. Diaphragm weight is related to body weight in both male (r = + 0.76) and female patients (r = +0.77) and is relatively larger in the former. Dissecting the diaphragm free of fat or freeze drying it does not appreciably improve the relationship between body weight and diaphragm weight. Diaphragm weight is better related to body weight than body length and is diminished in emphysema. Patients with emphysema weigh less. This is apparent with only moderate grades of emphysema, and there is no further loss of body weight as emphysema in the lung becomes more severe. The loss of diaphragm weight not only reflects the loss of body weight that occurs in emphysema, but the diaphragm is also less in weight than predicted from body weight. The diaphragm also appears abnormal on gross inspection in some patients with emphysema. Heart weight and diaphragm weight are related, probably because both are related to body weight.
对103名男性患者和81名女性患者的膈肌重量进行了研究，并对662名男性患者和431名女性患者的体重与肺气肿之间的关系进行了评估。男性（r = + 0.76）和女性患者（r = +0.77）的膈肌重量均与体重相关，且男性患者的膈肌重量相对更大。去除膈肌上的脂肪或将其冷冻干燥，对体重与膈肌重量之间的关系并无明显改善。膈肌重量与体重的相关性优于与体长的相关性，且在肺气肿患者中膈肌重量会减轻。肺气肿患者体重较轻。这在仅为中度肺气肿时就很明显，并且随着肺部肺气肿病情加重，体重不会进一步减轻。膈肌重量的减轻不仅反映了肺气肿患者体重的减轻，而且膈肌重量也低于根据体重预测的重量。在一些肺气肿患者中，肉眼检查时膈肌也显得异常。心脏重量与膈肌重量相关，可能是因为两者都与体重相关。
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