戊巴比妥对猫脑动脉收缩反应的影响。
Effects of pentobarbital on contractile responses of feline cerebral arteries.
作者信息
Edvinsson L, McCulloch J
出版信息
J Cereb Blood Flow Metab. 1981;1(4):437-40. doi: 10.1038/jcbfm.1981.48.
PMID:6948815
Abstract
The effects of pentobarbital on the contractile responses of isolated feline middle cerebral arteries have been examined. In the presence of pentobarbital (3 x 10(-4)M), the maximum contractions effected by potassium, noradrenaline, and prostaglandin F2 alpha were reduced by 37 +/- 3, 69 +/- 3, and 10 +/- 6%, respectively. The results caution against the use of pentobarbital as an anaesthetic agent in investigations of cerebrovascular reactivity.
摘要
已研究了戊巴比妥对离体猫大脑中动脉收缩反应的影响。在戊巴比妥（3×10⁻⁴M）存在的情况下，钾、去甲肾上腺素和前列腺素F2α引起的最大收缩分别降低了37±3%、69±3%和10±6%。这些结果警示在脑血管反应性研究中使用戊巴比妥作为麻醉剂时应谨慎。
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