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人类白细胞抗原B8抗原与抗磷脂酶A1同种免疫

HLA-B8 antigens and anti-PLa1 allo-immunization.

作者信息

Reznikoff-Etievant M F, Dangu C, Lobet R

出版信息

Tissue Antigens. 1981 Jul;18(1):66-8. doi: 10.1111/j.1399-0039.1981.tb01364.x.

DOI:10.1111/j.1399-0039.1981.tb01364.x
PMID:6949342
Abstract

HLA-A-B-C and DR typing was performed on sixteen individuals whose PLA1 platelet group was negative. Ten of them were immunostimulated with PLA1 antigen by pregnancy or transfusion; six of them were responders and developed an anti-PLA1 antibody. A high incidence of HLA-B8 antigen was observed in that group of responders. This observation is supported by five other cases of allo-immunization reported in previous papers.

摘要

对16名PLA1血小板组呈阴性的个体进行了HLA - A - B - C和DR分型。其中10人因怀孕或输血而受到PLA1抗原免疫刺激;他们中有6人产生反应并产生了抗PLA1抗体。在该反应者组中观察到HLA - B8抗原的高发生率。此前文献报道的其他5例同种免疫病例也支持了这一观察结果。

相似文献

1
HLA-B8 antigens and anti-PLa1 allo-immunization.人类白细胞抗原B8抗原与抗磷脂酶A1同种免疫
Tissue Antigens. 1981 Jul;18(1):66-8. doi: 10.1111/j.1399-0039.1981.tb01364.x.
2
The detection of platelet alloantibodies by flow cytometry.通过流式细胞术检测血小板同种抗体。
Transfusion. 1991 May;31(4):340-4. doi: 10.1046/j.1537-2995.1991.31491213300.x.
3
Alloimmunization to the PlA1 platelet antigen: results of a prospective study.对PlA1血小板抗原的同种免疫:一项前瞻性研究的结果。
Br J Haematol. 1990 Feb;74(2):209-15. doi: 10.1111/j.1365-2141.1990.tb02567.x.
4
[Immunization against the ZWa (PLA1) platelet antigen: group at risk, prevention of complications. Apropos of 132 cases].
Pathol Biol (Paris). 1986 Jun;34(6):783-7.
5
[Inhibition of platelet migration. A simple technic for typing of PLA1 and the detection of platelet allo- and autoantibodies].[血小板迁移的抑制。一种用于PLA1分型及检测血小板同种抗体和自身抗体的简单技术]
Rev Fr Transfus Immunohematol. 1978 Dec;21(5):1103-19. doi: 10.1016/s0338-4535(78)80007-5.
6
Quantitative determination of platelet surface alloantigens using a monoclonal probe.使用单克隆探针定量测定血小板表面同种抗原。
Hum Immunol. 1986 Mar;15(3):251-62. doi: 10.1016/0198-8859(86)90001-7.
7
[Platelet allo-antibodies identification strategies for preventing and managing platelet refractoriness].[预防和管理血小板输注无效的血小板同种抗体鉴定策略]
Transfus Clin Biol. 2014 Nov;21(4-5):193-206. doi: 10.1016/j.tracli.2014.08.140. Epub 2014 Sep 30.
8
Platelets from donors with consistently low HLA-B8, -B12, or -B35 expression do not undergo antibody-mediated internalization.表达 HLA-B8、B12 或 B35 持续低水平的供者血小板不会发生抗体介导的内化。
Blood. 2018 Jan 4;131(1):144-152. doi: 10.1182/blood-2017-07-799270. Epub 2017 Nov 1.
9
Autoreactive platelet antibody in post transfusion purpura.输血后紫癜中的自身反应性血小板抗体。
Aust N Z J Med. 1990 Apr;20(2):111-5. doi: 10.1111/j.1445-5994.1990.tb01284.x.
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HLA antigen and antibody association in platelet-alloimmunized patients.
Zhonghua Yi Xue Za Zhi (Taipei). 1993 May;51(5):329-32.

引用本文的文献

1
Posttransfusion purpura. A survey of 13 cases.输血后紫癜。13例病例调查。
Klin Wochenschr. 1986 Nov 17;64(22):1198-203. doi: 10.1007/BF01728461.