Brudevold F, Tehrani A, Bakhos Y
J Dent Res. 1982 Mar;61(3):456-9. doi: 10.1177/00220345820610030201.
The iodide permeability (Ip) of abraded bovine enamel increased after short exposure to an acid buffer and decreased after short exposure to a mineralizing solution. Intraoral exposure gave a marked decrease in Ip after one h and a continued lesser decrease after two and three h. In vitro exposure to fresh and dialyzed saliva and various undersaturated solutions indicated that the intraoral decrease was due to mineralization rather than to pellicle formation. Analysis of the data also indicated that part of the mineral formed intraorally was more loosely bound to the enamel than that formed from an inorganic mineralizing solution. The rapid rate of the initial phase of intraoral mineralization shown in this study reveals a powerful mechanism for protecting the dentition against demineralization.
磨损的牛牙釉质的碘通透性（Ip）在短时间暴露于酸性缓冲液后增加，而在短时间暴露于矿化溶液后降低。口腔内暴露1小时后Ip显著降低，2小时和3小时后持续有较小程度的降低。体外暴露于新鲜和透析唾液以及各种不饱和溶液表明，口腔内的降低是由于矿化而非薄膜形成。对数据的分析还表明，口腔内形成的部分矿物质与牙釉质的结合比由无机矿化溶液形成的矿物质更松散。本研究中显示的口腔内矿化初始阶段的快速速率揭示了一种保护牙列免于脱矿的强大机制。
