Buchner R
J Oral Rehabil. 1982 Jan;9(1):7-22. doi: 10.1111/j.1365-2842.1982.tb00530.x.
Advancement of the calcification front in the cartilage, which is a measure of the growth of the cartilage, can be determined by the administration of two dose bone-markers at specific intervals. It appears that growth still takes place in animals of 12-18 months. This growth is possible by the persistence of chondrogenic cells. The overall growth of the central part of the condyle amounts to about 2 mm over the period from 2 to 18 months. Raising of the bite in the rat has an obvious influence on the temporomandibular joint, and on the condyle in particular. Within a few days an increase of growth-rate of cartilage can be demonstrated. This extra growth is temporary, and the intensity and duration of the response is determined by the age of the animal. This adaptation is related to the presence of chondrogenic cells in the cartilaginous layer in the condyle.
软骨中钙化前沿的进展是软骨生长的一种衡量指标，可通过在特定间隔给予两种剂量的骨标志物来确定。似乎在12 - 18个月大的动物中仍会发生生长。这种生长是通过软骨生成细胞的持续存在实现的。在2至18个月期间，髁突中部的总体生长量约为2毫米。大鼠咬合升高对颞下颌关节，尤其是对髁突有明显影响。在几天内即可证明软骨生长速率增加。这种额外的生长是暂时的，反应的强度和持续时间取决于动物的年龄。这种适应性与髁突软骨层中软骨生成细胞的存在有关。
