Matsumoto T
Jpn J Antibiot. 1981 Nov;34(11):1465-9.
Cefmetazole (CMZ) was applied to the subjects with infectious skin disease of more than middle severe cases in the present study, and the following results were obtained. 1. The clinical effects were as follows: among 15 clinical cases, 1 remarkably effective and 14 effective cases were observed, with 100% of effectiveness. 2. Bacteriological effects were as follows: 11 strains of S. aureus and 4 strains of S. epidermidis were isolated and all of them disappeared by the administration of CMZ. 3. Sensitivity test using a disc method showed that good sensitivity of better than (++) was obtained by CMZ and CEZ for all tested bacteria. 4. CMZ showed excellent clinical effects on the subjects to which oral cephalosporins and penicillins were not effective. 5. No undesirable side effects ascribable to the CMZ administration were observed.
在本研究中，头孢美唑（CMZ）应用于中重度以上的感染性皮肤病患者，获得了以下结果。1. 临床疗效如下：15例临床病例中，观察到1例显效和14例有效，有效率为100%。2. 细菌学疗效如下：分离出11株金黄色葡萄球菌和4株表皮葡萄球菌，给予CMZ后所有菌株均消失。3. 纸片法药敏试验表明，CMZ和头孢唑林（CEZ）对所有受试细菌均显示出优于（++）的良好敏感性。4. CMZ对口服头孢菌素和青霉素无效的患者显示出优异的临床效果。5. 未观察到因使用CMZ而产生的不良副作用。
