Rucksan B E, Wells G A, Lewis G
Vet Rec. 1978 Aug 19;103(8):153-5. doi: 10.1136/vr.103.8.153.
Newly weaned pigs were given Solanum malacoxylon at dose rates of 0.2 and 1.0 g per kg body-weight per week for eight weeks. The Solanum malacoxylon was given either as an aqueous extract (SM) or as an aqueous extract incubated with fresh rumen liquor (SMLR). Tubulonephrosis, dose related in severity, was evident in all treated pigs and focal calcification in kidney and lung occurred in pigs receiving the higher dose rate. There was a marked hypercalcaemia and hypophosphataemia over the trial period; the latter feature was in contrast with the hyperphosphataemia produced in sheep. Incubation of SM with rumen liquor enhanced hypophosphataemia at both dose levels in the pig but its effect on serum calcium was equivocal.
给刚断奶的仔猪按每周每千克体重0.2克和1.0克的剂量投喂刺萼龙葵，持续八周。刺萼龙葵以水提取物（SM）或与新鲜瘤胃液一起孵育的水提取物（SMLR）形式投喂。所有接受治疗的猪均出现了剂量相关的严重肾小管肾病，接受较高剂量率的猪的肾脏和肺部出现了局灶性钙化。在试验期间，出现了明显的高钙血症和低磷血症；后一特征与绵羊产生的高磷血症形成对比。在猪中，SM与瘤胃液孵育在两个剂量水平上均增强了低磷血症，但其对血清钙的影响不明确。
