Glass J D, Crowder J V, Kennerdell J S, Merikangas J R
Electroencephalogr Clin Neurophysiol. 1977 Aug;43(2):207-17. doi: 10.1016/0013-4694(77)90128-6.
The visually evoked potential (VEP) was recorded from the scalp overlying precentral and occipital cortex in three monocularly deprived humans. The subjects had defects of the globe from birth that effectively created a condition of diffuse light rearing in one eye. In subject, BER, a 19-year-old with a recently removed congenital cataract, the occipital response evoked from the deprived eye was reduced by 53% compared with the response evoked from the good eye. In subject GUZ, age 20 with a congenital cataract, the occipital response evoked from the deprived eye was actually larger by 20% than was the response evoked from the good eye. For UTZ, age 5 with whitish cellular debri in the anterior vitreous of the eye, the occipital response evoked from the deprived eye was only 4% smaller than the response evoked from his good eye. In all three subjects, the precentral response evoked from the deprived eye was reduced in amplitude compared with the precentral response evoked from the good eye. In terms of relative effect of the deprivation upon the VEP from the two recording sites, the precentral VEP was altered to a greater extent than was the occipital VEP. These findings indicate that diffuse light rearing can affect the pathways projecting to precentral cortex independently of the specific visual pathways.
在三名单眼剥夺者中，从中央前回和枕叶皮质上方的头皮记录视觉诱发电位（VEP）。这些受试者自出生起就存在眼球缺陷，有效地造成了一只眼睛处于漫射光饲养的状况。在受试者BER中，一名19岁的近期摘除先天性白内障患者，与好眼诱发的反应相比，剥夺眼诱发的枕叶反应降低了53%。在受试者GUZ中，一名20岁的先天性白内障患者，剥夺眼诱发的枕叶反应实际上比好眼诱发的反应大20%。对于UTZ，一名5岁的眼前玻璃体有白色细胞碎屑的患者，剥夺眼诱发的枕叶反应仅比好眼诱发的反应小4%。在所有三名受试者中，与好眼诱发的中央前回反应相比，剥夺眼诱发的中央前回反应幅度降低。就剥夺对两个记录部位VEP的相对影响而言，中央前回VEP的改变程度大于枕叶VEP。这些发现表明，漫射光饲养可独立于特定视觉通路影响投射到中央前回皮质的通路。
